Chromogranin A (CHGA) Rabbit Monoclonal Antibody [Clone ID: R04-4J4]

Specifications

Product Data
Clone Name	R04-4J4
Applications	WB
Recommend Dilution	WB: 1/1000
Reactivity	Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human Chromogranin A
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 51 kDa; Observed MW: 92 kDa
Gene Name	chromogranin A
Database Link	UniProt ID P10645
Background	Swiss-Prot Acc.P10645.Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas.CaTatin: Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist (PubMed:15326220). Displays antibacterial activity against Gram-positive bacteria S.aureus and M.luteus, and Gram-negative bacteria E.coli and P.aeruginosa (PubMed:15723172 and PubMed:24723458). Can induce mast cell migration, degranulation and production of cytokines and chemokines (PubMed:21214543). Acts as a potent scavenger of free radicals in vitro (PubMed:24723458). May play a role in the regulation of cardiac function and blood pressure (PubMed:18541522).
Synonyms	CgA; SP-I
Reference Data

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