FOXO4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IF, IP, WB
Recommend Dilution	WB: 1/1000-1/2000 ICC/IF: 1/50-1/200 IP: 1/50 FC: 1/100
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthesized peptide derived from human FoxO4
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	65kDa
Gene Name	forkhead box O4
Database Link	Entrez Gene 4303 Human UniProt ID P98177
Background	Swiss-Prot Acc.P98177.The Forkhead family of transcription factors is involved in tumorigenesis of rhabdomyosarcoma and acute leukemias. Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.
Synonyms	AFX; AFX1; MGC120490; MLLT7
Reference Data

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