H3FT (HIST3H3) Mouse Monoclonal Antibody [Clone ID: 10F10-1B8-4H3]

Specifications

Product Data
Clone Name	10F10-1B8-4H3
Applications	IHC
Recommend Dilution	IHC: 1/100-200
Reactivity	Human, Rat, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide conjugated to KLH. (Acetylated)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	15kDa
Gene Name	histone cluster 3, H3
Database Link	Entrez Gene 8290 Human UniProt ID P68431
Background	Swiss-Prot Acc.P68431.Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.MiscellaneousThis histone is only present in mammals and is enriched in acetylation of Lys-15 and dimethylation of Lys-10 (H3K9me2).
Synonyms	H3.4; H3/g; H3/t; H3FT; H3t; MGC126886; MGC126888
Reference Data

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