PTCH1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	WB: 1/500-1/2000 IHC: 1/100-1/300 ELISA: 1/10000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against synthesized peptide derived from human Patched. AA range:1-50
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Observed MW (kDa):160
Gene Name	patched 1
Database Link	Entrez Gene 5727 Human UniProt ID Q13635
Background	Swiss-Prot Acc.Q13635.Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
Synonyms	BCNS; FLJ26746; FLJ42602; HPE7; NBCCS; OTTHUMP00000021709; OTTHUMP00000021710; patched; PTC; PTC1; PTCH; PTCH11
Reference Data

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