SQSTM1 Rabbit Polyclonal Antibody
CAT#: TA385312
SQSTM1/p62 Rabbit polyclonal Antibody
Size: 20 ul
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Specifications
Product Data | |
Applications | FC, IF, WB |
Recommend Dilution | WB: 1/1000 ICC/IF: 1/50-1/200 FC: 1/50 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A synthesized peptide derived from human p62/SQSTM1 |
Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration | lot specific |
Purification | Affinity Chromatography |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Predicted Protein Size | 62kDa |
Gene Name | sequestosome 1 |
Database Link | |
Background | Swiss-Prot Acc.Q13501.Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. |
Synonyms | A170; EBIAP; ORCA; OSIL; p60; p62; p62B; PDB3; ZIP3 |
Reference Data |
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