VDAC1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1/500-1/2000 IHC: 1/50-1/200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthesized peptide derived from human VDAC1
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	31kDa
Gene Name	voltage dependent anion channel 1
Database Link	Entrez Gene 7416 Human UniProt ID P21796
Background	Swiss-Prot Acc.P21796.Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria. In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics.
Synonyms	hVDAC1; MGC111064; OTTHUMP00000159381; OTTHUMP00000165946; PORIN; PORIN-31-HL; VDAC; VDAC-1
Reference Data

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