RAGE (AGER) Rabbit Monoclonal Antibody [Clone ID: 2A11]

Specifications

Product Data
Clone Name	2A11
Applications	ELISA, FC, IF, IHC, WB
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Human RAGE protein.
Specificity	2A11 is specific for the V-domain of human advanced glycosylation end product-specific receptor. It recognises both the glycosylated and non-glycosylated forms. ELISA confirmed the specificity of 2A11 for the V-domain of RAGE, with a binding affinity (Kd) of 7.6 nM. ELISA was also used to confirm that the binding of 2A11 to RAGE is glycosylation independent. In SPR experiments the Kd of 2A11 binding to RAGE was determined as 0.38 nM. Flow cytometry and immunochemistry were used to visualise the binding of 2A11 to HEK-RAGE cells.
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	advanced glycosylation end product-specific receptor
Database Link	Entrez Gene 177 Human UniProt ID Q15109
Synonyms	MGC22357; RAGE
Note	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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