Anti-CSF1R antibody(DM106), Rabbit mAb
CAT#: TA389324
Anti-CSF1R antibody(DM106), Rabbit mAb
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CNY 6,150.00
货期*
2周
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Specifications
Product Data | |
Clone Name | DM106 |
Applications | ELISA, FC |
Recommend Dilution | ELISA 1:5000-10000 Flow Cyt 1:100 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Formulation | 1XPBS |
Concentration | Lot specific |
Purification | Purified from cell culture supernatant by affinity chromatography |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature. |
Background | The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma. |
Synonyms | CSF1R,C-FMS,CD115,CSFR,FIM2,FMS,M-CSFR |
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