Anti-BCL2L1 antibody(DM189), Rabbit mAb

CAT#: TA389405

Anti-BCL2L1 antibody(DM189), Rabbit mAb



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CNY 6,150.00


货期*
2周

规格
    • 100 ug

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Specifications

Product Data
Clone Name DM189
Applications ELISA, FC
Recommend Dilution ELISA 1:5000-10000
Flow Cyt 1:100
Reactivity Human
Host Rabbit
Clonality Monoclonal
Formulation 1XPBS
Concentration Lot specific
Purification Purified from cell culture supernatant by affinity chromatography
Conjugation Unconjugated
Storage Condition Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Background The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
Synonyms Bcl-X, BCL-XL/S, BCL2L, BCLX, PPP1R52
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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