CD59 Rabbit Polyclonal Antibody

CAT#: TA392467

CD59 polyclonal antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,350.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:1000~1:2000
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein of human CD59.
Specificity CD59 polyclonal antibody detects endogenous levels of CD59 protein.
Formulation Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Concentration 1mg/ml
Conjugation Unconjugated
Storage Condition Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size ~17 kDa
Gene Name CD59 molecule
Background Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
Synonyms 1F5 antigen; 20 kDa homologous restriction factor; CD59; CD59 glycoprotein; HRF-20; HRF20; MAC-inhibitory protein; MAC-IP; MACIF; MEM43 antigen; Membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; MIRL; Protectin
Note For research use only, not for use in diagnostic procedure.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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