RSK1 p90 (RPS6KA1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:1000~1:2000 IHC: 1:50~1:200
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic phosphopeptide derived from human Rsk-1 around the phosphorylation site of Serine 380.
Specificity	p-Rsk-1 (S380) polyclonal antibody detects endogenous levels of Rsk-1 protein only when phosphorylated at Ser380.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 90 kDa
Gene Name	ribosomal protein S6 kinase A1
Database Link	Entrez Gene 6195 Human UniProt ID Q15418
Background	The family of ribosomal S6 kinases (Rsks), designated Rsk-1 (or MAPKAP kinase-1), Rsk-2 and Rsk-3, are intracellular serine/threonine kinases that are important signaling intermediates in response to a broad range of ligand activated receptor tyrosine kinases. A unique feature common to the members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. An additional Rsk protein, Rsk-4, shows a high level of homology to the three previously isolated members of the human Rsk family. Rsk-4 is most abundantly expressed in brain and kidney and plays a role in normal neuronal development.
Synonyms	90 kDa ribosomal protein S6 kinase 1; MAPK-activated protein kinase 1a; MAPKAPK-1a; MAPKAPK1A; MAPKAP kinase 1a; MAP kinase-activated protein kinase 1a; p90-RSK 1; p90RSK1; p90S6K; Ribosomal protein S6 kinase alpha-1; Ribosomal S6 kinase 1; RPS6KA1; RSK-1; RSK1; S6K-alpha-1; S6K-α1; S6K α1; S6Kα1
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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