Androgen Receptor (AR) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1:2000~1:5000 IHC: 1:50~1:200 IF: 1:50~1:200
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to Human AR.
Specificity	AR polyclonal antibody detects endogenous levels of AR protein.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 140 kDa
Gene Name	androgen receptor
Database Link	Entrez Gene 367 Human UniProt ID P10275
Background	Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding. This promotes nuclear localization and binding of AR to androgen response elements in androgen target genes. Research studies have shown that AR plays a crucial role in several stages of male development and the progression of prostate cancer.
Synonyms	Androgen receptor; AR; DHTR; Dihydrotestosterone receptor; NR3C4; Nuclear receptor subfamily 3 group C member 4
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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