EIF3S3 (EIF3H) Rabbit Polyclonal Antibody
CAT#: TA392598
EIF3H polyclonal antibody
Size: 25 ul
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CNY 1,999.00
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Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommend Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Reactivity | Human, Rat, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide, corresponding to Human EIF3H. |
Specificity | EIF3H polyclonal antibody detects endogenous levels of EIF3H protein. |
Formulation | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Concentration | 1mg/ml |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Predicted Protein Size | ~ 40 kDa |
Gene Name | eukaryotic translation initiation factor 3 subunit H |
Database Link | |
Background | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. |
Synonyms | eIF-3-gamma; eIF3 p40 subunit; EIF3H; eIF3h; EIF3S3; Eukaryotic translation initiation factor 3 subunit 3; Eukaryotic translation initiation factor 3 subunit H |
Note | For research use only, not for use in diagnostic procedure. |
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