BCKDH kinase (BCKDK) Rabbit Polyclonal Antibody

CAT#: TA392719

BCKDK (E41) polyclonal antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,350.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:500~1:1000 IHC: 1:50~1:200 IP 1:50 - 1:100
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids 21-70 of Human BCKDK.
Specificity BCKDK (E41) polyclonal antibody detects endogenous levels of BCKDK protein.
Formulation Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration 1mg/ml
Conjugation Unconjugated
Storage Condition Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size ~ 46 kDa
Gene Name branched chain ketoacid dehydrogenase kinase
Background BCKDK (branched chain ketoacid dehydrogenase kinase), also known as BCKDHKIN, is a 412 amino acid mitochondrial matrix protein that exists as a monomer and contains one histidine kinase domain. Expressed ubiquitously, BCKDK catalyzes the ATP-dependent phosphorylation and subsequent inactivation of the branched-chain α-ketoacid dehydrogenase (BCKD) complex, a regulatory enzyme complex that plays a crucial role in the catabolic pathways of valine, leucine and isoleucine. Specifically, the BCKD complex functions as the second enzyme in branched-chain amino acid (BCAA) catabolism, effectively catalyzing the irreversible oxidative decarboxylation of BCAAs. Due to the ability of BCKDK to regulate the activity of the BCKD complex, BCKDK plays an essential role in the catabolic pathways of branched-chain amino acid metabolism.
Synonyms BCKD-kinase; BCKDHKIN; Bckdk; BCKD kinase; Branched-chain alpha-ketoacid dehydrogenase kinase; Branched chain alpha keto acid dehydrogenase kinase; Branched chain ketoacid dehydrogenase kinase; mitochondrial
Note For research use only, not for use in diagnostic procedure.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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