Myeloid zinc finger 1 (MZF1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 5-55 of Human MZF-1.
Specificity	MZF-1 (D10) pAb detects endogenous levels of MZF-1 protein.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 82 kDa
Gene Name	myeloid zinc finger 1
Database Link	Entrez Gene 7593 Human UniProt ID P28698
Background	Zinc finger genes encode metal-binding proteins are transcriptional regulators of other genes. Myeloid zinc finger 1 (MZF-1), also designated zinc finger protein 42, and transcription factor ZBP-89, also designated zinc finger protein 148, belong to the Krüppel C2H2-type zinc-finger protein family. The gene encoding for the MZF-1 protein maps to chromosome 19q13.43, while the gene encoding for ZBP-89 is localized on chromosome 3q21.2. These proteins are nuclear proteins involved in the regulation of transcriptional events. MZF-1 regulates transcription during hemopoietic development and plays a role in myeloid cell differentiation. It regulates the CD34 promoter in a tissue-specific manner. MZF-1 and FHL3 can form a complex of high molecular mass with other proteins in the nucleus. MZF-1 is induced by retinoic acid and is primarily expressed in differentiating myeloid cells.
Synonyms	Myeloid zinc finger 1; MZF; MZF-1; MZF1; Zinc finger and SCAN domain-containing protein 6; Zinc finger protein 42; ZNF42; ZSCAN6
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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