TFIIE beta (GTF2E2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 153-213 of Human TFIIE-β.
Specificity	TFIIE-β (K183) pAb detects endogenous levels of TFIIE-β protein.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 33 kDa
Gene Name	general transcription factor IIE subunit 2
Database Link	Entrez Gene 2961 Human UniProt ID P29084
Background	The general transcription factor TFIIE consists of two subunits, α and β, and plays essential roles in transcription.Structure-function studies indicate that TFIIE has three-winged helix (WH) motifs, with one in TFIIEα and two in TFIIEβ. by binding to the clamp region of RNA polymerase II, TFIIEα-WH promotes the conformational change that transforms the promoter-bound inactive preinitiation complex to the active complex.
Synonyms	General transcription factor IIE subunit 2; GTF2E2; TF2E2; TFIIE-beta; Transcription initiation factor IIE subunit beta
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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