ADNP Rabbit Polyclonal Antibody
CNY 1,999.00
CNY 3,350.00
货期*
2周
规格
经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 1:500~1:1000 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide, corresponding Human ADNP. |
Specificity | ADNP polyclonal antibody detects endogenous levels of ADNP protein. |
Formulation | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Concentration | 1mg/ml |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Predicted Protein Size | ~ 123 kDa |
Gene Name | activity-dependent neuroprotector homeobox |
Database Link | |
Background | Activity-dependent neuroprotector (ADNP), also designated activity-dependent neuroprotective protein, is a nuclear protein that functions as a putative transcription factor and may participate in normal growth and cancer proliferation. ADNP is a highly conserved vasoactive intestinal peptide (VIP) responsive gene that is expressed profusely in the brain (primarily cerebellum and cortex regions) and is crucial for brain formation and embryonic development. ADNP is also highly expressed in kidney, placenta, heart, skeletal muscle, breast, and colon cancer tissues. Studies indicate that neuroprotection by subpicomolar PACAP38 might be mediated partially by expression of ADNP. A correlation between brain injuries and elevated ADNP levels indicates a potential involvement of ADNP in an endogenous compensatory mechanism. |
Synonyms | Activity-dependent neuroprotective protein; Activity-dependent neuroprotector homeobox protein; ADNP; ADNP1; KIAA0784 |
Note | For research use only, not for use in diagnostic procedure. |
Reference Data |
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