ARHGAP17 Rabbit Polyclonal Antibody

CAT#: TA392849

ARHGAP17 (T363) polyclonal antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,350.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:500~1:1000
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids 845-905 of Human RoXaN.
Specificity ARHGAP17(T363) pAb detects endogenous levels of ARHGAP17 protein.
Formulation Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration 1mg/ml
Conjugation Unconjugated
Storage Condition Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size ~ 130 kDa
Gene Name Rho GTPase activating protein 17
Background GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in down regulation of their active form. ARHGAP17 (Rho GTPase activating protein 17), also known as RICH1, WBP15, MST066, MST110, NADRIN, PP4534, RICH1B, MSTP038, MSTP066 or MSTP110, is a ubiquitously expressed peripheral membrane protein whose expression is highest in heart and placenta. ARHGAP17 is involved in the maintenance of tight junctions by regulating the activity of Cdc42, thereby playing a central role in apical polarity of epithelial cells. Containina a BAR domain and a Rho-GAP domain, ARHGAP17 acts as a GTPase activator for the Cdc42 GTPase by converting it to an inactive GDP-bound state. ARHGAP17 may also participate in the Ca2+-dependent regulation of exocytosis by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of cortical actin filaments. ARHGAP17 exists as seven alternative splice variants.
Synonyms KIAA1031; Rotavirus 'X'-associated non-structural protein; RoXaN; ZC3H7B; Zinc finger CCCH domain-containing protein 7B
Note For research use only, not for use in diagnostic procedure.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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