Phospho-EIF4EBP1 Rabbit Polyclonal Antibody
CNY 7,740.00
货期*
5周
规格
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB,1:2000 - 1:6000 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A synthetic phosphorylated peptide around T70 of human Phospho-eIF4EBP1-T70 (NP_004086.1). |
Formulation | Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 13kDa - Observed MW: 15-20kDa |
Gene Name | eukaryotic translation initiation factor 4E binding protein 1 |
Database Link | |
Background | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. |
Synonyms | 4E-BP1; 4EBP1; BP-1; PHAS-I |
Reference Data |
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