Phospho-Rb (RB1) Rabbit Polyclonal Antibody

CAT#: TA420114

Phospho-RB-S780 Rabbit mAb



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CNY 7,740.00


货期*
5周

规格
    • 100 ul

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Specifications

Product Data
Applications WB
Recommend Dilution WB,1:1000 - 1:5000
Reactivity Human, Rat
Host Rabbit
Clonality Polyclonal
Immunogen A phospho synthetic peptide corresponding to residues surrounding S780 of Human RB.
Formulation Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size 106kDa - Observed MW: 110kDa
Gene Name RB transcriptional corepressor 1
Background The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Synonyms OSRC; p105-Rb; p110-RB1; pp110; PPP1R130; pRb; RB
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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