Neurotrophin 4 (NTF4) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2E8]

Specifications

Product Data
Clone Name	OTI2E8
Applications	IF, IHC, WB
Recommend Dilution	WB 1:5000, IHC 1:50, IF 1:50
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 81-210 human NT4 (NP_006170) produced in E.coli.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	22.2 kDa
Gene Name	neurotrophin 4
Database Link	NP_006170 Entrez Gene 25730 RatEntrez Gene 4909 Human UniProt ID P34130
Background	NT4 is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of NT4 is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NT4-deficient mice only show minor cellular deficits and develop normally to adulthood.
Synonyms	GLC1O; GLC10; NT-4; NT-4/5; NT-5; NT4; NT5; NTF5
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	MAPK signaling pathway, Neurotrophin signaling pathway

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