beta Catenin (CTNNB1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3G4]

CAT#: TA500240BM

Anti-Beta-catenin mouse monoclonal antibody, clone OTI3G4 (formerly 3G4), HRP conjugated

Conjugation: Unconjugated Biotin HRP



  View other "OTI3G4" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

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经常一起买 (3)
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Recombinant protein of human catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), 20 µg
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Transient overexpression lysate of catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 1
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Specifications

Product Data
Clone Name OTI3G4
Applications IF, WB
Recommend Dilution WB 1:1000
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Recombinant protein expressed in E.coli corresponding to amino acids 531-781 of human beta-catenin
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Condition Store at -20°C as received.
Predicted Protein Size 85.3 kDa
Gene Name catenin beta 1
Background Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete
Synonyms armadillo; CTNNB; MRD19
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
Protein Pathways Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Basal cell carcinoma, Colorectal cancer, Endometrial cancer, Focal adhesion, Leukocyte transendothelial migration, Melanogenesis, Pathogenic Escherichia coli infection, Pathways in cancer, Prostate cancer, Thyroid cancer, Tight junction, Wnt signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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