alpha 1 Antitrypsin (SERPINA1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI8E3]

Specifications

Product Data
Clone Name	OTI8E3
Applications	IHC, IP, WB
Recommend Dilution	WB 1:500~1000, IHC 1:150, IP 2ug/500ul
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human SERPINA1 (NP_000286) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	44.3 kDa
Gene Name	serpin family A member 1
Database Link	NP_000286 Entrez Gene 5265 Human UniProt ID P01009
Background	The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Synonyms	A1A; A1AT; AAT; alpha1AT; PI; PI1; PRO2275
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways	Complement and coagulation cascades

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