Melanoma gp100 (PMEL) Mouse Monoclonal Antibody [Clone ID: OTI7B2]

Specifications

Product Data
Clone Name	OTI7B2
Applications	FC, IF
Recommend Dilution	IF 1:100, Flow 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human SILV (NP_008859) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	70.3 kDa
Gene Name	premelanosome protein
Database Link	NP_008859 Entrez Gene 6490 Human UniProt ID P40967
Background	Could be a melanogenic enzyme. Could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
Synonyms	D12S53E; gp100; ME20; ME20-M; ME20M; P1; P100; PMEL17; SI; SIL; SILV
Reference Data
Protein Families	Secreted Protein, Transmembrane

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