Aurora C (AURKC) Mouse Monoclonal Antibody [Clone ID: OTI10A7]

Specifications

Product Data
Clone Name	OTI10A7
Applications	IF, WB
Recommend Dilution	WB 1:500, IF 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full-length protein expressed in 293T cell transfected with human AURKC expression vector
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.85 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	35.6 kDa
Gene Name	aurora kinase C
Database Link	NP_001015878 Entrez Gene 6795 Human UniProt ID Q9UQB9
Background	This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
Synonyms	AIE2; AIK3; ARK3; AurC; aurora-C; HEL-S-90; SPGF5; STK13
Reference Data
Protein Families	Druggable Genome, Protein Kinase

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