IBRDC2 (RNF144B) Mouse Monoclonal Antibody [Clone ID: OTI10A12]

Specifications

Product Data
Clone Name	OTI10A12
Applications	WB
Recommend Dilution	WB 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-256 of human RNF144B (NP_877434) produced in E. coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	33.7 kDa
Gene Name	ring finger protein 144B
Database Link	NP_877434 Entrez Gene 218215 MouseEntrez Gene 255488 Human UniProt ID Q7Z419
Background	E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism.
Synonyms	bA528A10.3; IBRDC2; p53RFP; PIR2
Reference Data
Protein Families	Transmembrane

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