BHMT Mouse Monoclonal Antibody [Clone ID: OTI3E11]

Specifications

Product Data
Clone Name	OTI3E11
Applications	FC, IF, IHC, WB
Recommend Dilution	IHC 1:200, WB: 1:200
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human BHMT (NP_001704) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.93 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	45 kDa
Gene Name	betaine--homocysteine S-methyltransferase
Database Link	NP_001704 Entrez Gene 12116 MouseEntrez Gene 81508 RatEntrez Gene 635 Human UniProt ID Q93088
Background	This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed.
Synonyms	BHMT1; HEL-S-61p
Reference Data
Protein Pathways	Cysteine and methionine metabolism, Glycine, serine and threonine metabolism, Metabolic pathways

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