TUBA8 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2G6]

Specifications

Product Data
Clone Name	OTI2G6
Applications	IF, IHC, IP, WB
Recommend Dilution	WB 1:2000, IHC: 1:50-1:150, IF 1:100, Flow 1:100
Reactivity	Human, Dog, Rat, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human TUBA8(NP_061816) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	50.1 kDa
Gene Name	tubulin alpha 8
Database Link	NP_061816 Entrez Gene 500377 RatEntrez Gene 486762 DogEntrez Gene 710378 MonkeyEntrez Gene 51807 Human UniProt ID Q9NY65
Background	Microtubules are cylindrical tubes of 20-25 nm in diameter. They are composed of protofilaments which are in turn composed of alpha- and beta-tubulin polymers. Each microtubule is polarized, at one end alpha-subunits are exposed (-) and at the other beta-subunits are exposed (+). Microtubules act as a scaffold to determine cell shape, and provide a backbone for cell organelles and vesicles to move on, a process that requires motor proteins. The major microtubule motor proteins are kinesin, which generally moves towards the (+) end of the microtubule, and dynein, which generally moves towards the (-) end. Microtubules also form the spindle fibers for separating chromosomes during mitosis.
Synonyms	TUBAL2
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Gap junction, Pathogenic Escherichia coli infection

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