Aminoacylase 1 (ACY1) Mouse Monoclonal Antibody [Clone ID: OTI2B5]
CAT#: TA503191S
ACY1 (Aminoacylase 1) mouse monoclonal antibody, clone OTI2B5 (formerly 2B5)
Size: 100 ul
View other "OTI2B5" antibodies (6)
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CNY 800.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | OTI2B5 |
Applications | FC, WB |
Recommend Dilution | WB 1:2000, FLOW 1:100 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human ACY1(NP_000657) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.78 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 45.7 kDa |
Gene Name | aminoacylase 1 |
Database Link | |
Background | This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18. [provided by RefSeq] |
Synonyms | ACY-1; ACY1D; HEL-S-5 |
Reference Data | |
Protein Families | Protease |
Protein Pathways | Arginine and proline metabolism, Metabolic pathways |
Documents
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF503191 | Carrier-free (BSA/glycerol-free) ACY1 mouse monoclonal antibody, clone OTI2B5 (formerly 2B5) |
CNY 3,999.00 |
|
TA503191 | ACY1 (Aminoacylase 1) mouse monoclonal antibody, clone OTI2B5 (formerly 2B5) |
CNY 1,999.00 |
|
TA503191AM | ACY1 (Aminoacylase 1) mouse monoclonal antibody, clone OTI2B5 (formerly 2B5), Biotinylated |
CNY 3,990.00 |
|
TA503191BM | ACY1 (Aminoacylase 1) mouse monoclonal antibody, clone OTI2B5 (formerly 2B5), HRP conjugated |
CNY 3,990.00 |
|
TA600053 | ACY1 mouse monoclonal capture antibody, validated for ELISA and Luminex assays |
CNY 2,600.00 |
|
TA700052 | ACY1 biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays |
CNY 2,700.00 |
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