Aminoacylase 1 (ACY1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2B5]

CAT#: TA503191BM

ACY1 (Aminoacylase 1) mouse monoclonal antibody, clone OTI2B5 (formerly 2B5), HRP conjugated

Conjugation: Unconjugated Biotin HRP



  View other "OTI2B5" antibodies (6)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Clone Name OTI2B5
Applications FC, WB
Recommend Dilution WB 1:2000, FLOW 1:100
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human ACY1(NP_000657) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Condition Store at -20°C as received.
Predicted Protein Size 45.7 kDa
Gene Name aminoacylase 1
Background This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18. [provided by RefSeq]
Synonyms ACY-1; ACY1D; HEL-S-5
Reference Data
Protein Families Protease
Protein Pathways Arginine and proline metabolism, Metabolic pathways
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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