Aminoacylase 1 (ACY1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI16C1]

CAT#: TA503228AM

ACY1 (Aminoacylase 1) mouse monoclonal antibody, clone OTI16C1 (formerly 16C1), Biotinylated

Conjugation: Unconjugated Biotin HRP



  View other "OTI16C1" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

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经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Recombinant protein of human aminoacylase 1 (ACY1), 20 µg
    • 20 ug

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Transient overexpression lysate of aminoacylase 1 (ACY1)
    • 100 ug

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Specifications

Product Data
Clone Name OTI16C1
Applications FC, IHC, WB
Recommend Dilution WB 1:500, IHC 1:150, FLOW 1:100
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human ACY1(NP_000657) produced in HEK293 cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Condition Store at -20°C as received.
Predicted Protein Size 45.7 kDa
Gene Name aminoacylase 1
Background This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18. [provided by RefSeq]
Synonyms ACY-1; ACY1D; HEL-S-5
Reference Data
Protein Families Protease
Protein Pathways Arginine and proline metabolism, Metabolic pathways
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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