Aminoacylase 1 (ACY1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI16C1]
CAT#: TA503228AM
ACY1 (Aminoacylase 1) mouse monoclonal antibody, clone OTI16C1 (formerly 16C1), Biotinylated
Conjugation: Unconjugated HRP
View other "OTI16C1" antibodies (4)
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CNY 3,990.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | OTI16C1 |
Applications | FC, IHC, WB |
Recommend Dilution | WB 1:500, IHC 1:150, FLOW 1:100 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human ACY1(NP_000657) produced in HEK293 cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 45.7 kDa |
Gene Name | aminoacylase 1 |
Database Link | |
Background | This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18. [provided by RefSeq] |
Synonyms | ACY-1; ACY1D; HEL-S-5 |
Reference Data | |
Protein Families | Protease |
Protein Pathways | Arginine and proline metabolism, Metabolic pathways |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF503228 | Carrier-free (BSA/glycerol-free) ACY1 mouse monoclonal antibody, clone OTI16C1 (formerly 16C1) |
CNY 3,999.00 |
|
TA503228 | ACY1 (Aminoacylase 1) mouse monoclonal antibody, clone OTI16C1 (formerly 16C1) |
CNY 1,999.00 |
|
TA503228BM | ACY1 (Aminoacylase 1) mouse monoclonal antibody, clone OTI16C1 (formerly 16C1), HRP conjugated |
CNY 3,990.00 |
|
TA503228S | ACY1 (Aminoacylase 1) mouse monoclonal antibody, clone OTI16C1 (formerly 16C1) |
CNY 800.00 |
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