Acetyl CoA synthetase (ACSS2) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3B12]

Specifications

Product Data
Clone Name	OTI3B12
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human ACSS2(NP_061147) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Predicted Protein Size	78.4 kDa
Gene Name	acyl-CoA synthetase short chain family member 2
Database Link	NP_061147 Entrez Gene 60525 MouseEntrez Gene 311569 RatEntrez Gene 55902 Human UniProt ID Q9NR19
Background	This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
Synonyms	ACAS2; ACECS; ACS; ACSA; dJ1161H23.1
Reference Data
Protein Pathways	Glycolysis / Gluconeogenesis, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism

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