FMRP (FMR1) Mouse Monoclonal Antibody [Clone ID: OTI1C6]
CAT#: TA504290
FMR1 (FMRP ) mouse monoclonal antibody, clone OTI1C6 (formerly 1C6)
Size: 30 ul
Formulation: Carrier-Free
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CNY 1,999.00
CNY 2,700.00
Cited in 2 publications. |
Product images
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | OTI1C6 |
Applications | FC, IF, IHC, WB |
Recommend Dilution | WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100 |
Reactivity | Human, Dog, Rat, Monkey, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 36-279 of human FMR1(NP_002015) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 71 kDa |
Gene Name | FMRP translational regulator 1 |
Database Link | |
Background | The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010] |
Synonyms | FMRP; FRAXA; POF; POF1; POFX |
Reference Data | |
Protein Families | Druggable Genome |
Citations (2)
The use of this Antibodies has been cited in the following citations: |
---|
HOXA cluster antisense RNA 2 elevates KIAA1522 expression through microRNA‐520d‐3p and insulin like growth factor 2 mRNA binding protein 3 to promote the growth of vascular smooth muscle cells in thoracic aortic aneurysm
,null,
ESC Heart Failure
,PubMed ID 35730141
[FMR1]
|
A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14
,Zhou, LT;Ye, SH;Yang, HX;Zhou, YT;Zhao, QH;Sun, WW;Gao, MM;Yi, YH;Long, YS;,
Neuroscience
,PubMed ID 28257890
[FMR1]
|
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF504290 | Carrier-free (BSA/glycerol-free) FMR1 mouse monoclonal antibody, clone OTI1C6 (formerly 1C6) |
CNY 3,999.00 |
|
TA504290AM | FMR1 mouse monoclonal antibody,clone 1C6, Biotinylated |
CNY 3,990.00 |
|
TA504290BM | FMR1 mouse monoclonal antibody,clone 1C6, HRP conjugated |
CNY 3,990.00 |
|
TA504290S | FMR1 (FMRP ) mouse monoclonal antibody, clone OTI1C6 (formerly 1C6) |
CNY 800.00 |