DEF6 Mouse Monoclonal Antibody [Clone ID: OTI2C11]

Specifications

Product Data
Clone Name	OTI2C11
Applications	IF, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150, IF 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human DEF6(NP_071330) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	73.7 kDa
Gene Name	DEF6 guanine nucleotide exchange factor
Database Link	NP_071330 Entrez Gene 23853 MouseEntrez Gene 309642 RatEntrez Gene 50619 Human UniProt ID Q9H4E7
Background	DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]). [supplied by OMIM]
Synonyms	IBP; SLAT; SWAP70L
Reference Data
Protein Families	Druggable Genome

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