IL1 beta (IL1B) Mouse Monoclonal Antibody [Clone ID: OTI3E1]
CAT#: TA506443
IL1B mouse monoclonal antibody, clone OTI3E1 (formerly 3E1)
Size: 30 ul
Formulation: Carrier-Free
View other "OTI3E1" antibodies (4)
Need it in bulk or conjugated?
Get a free quote
CNY 1,999.00
CNY 2,700.00
Cited in 5 publications. |
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | OTI3E1 |
Applications | IF, IHC, WB |
Recommend Dilution | WB 1:1000~4000, IHC 1:150, IF 1:100 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human IL1B(NP_000567) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 30.6 kDa |
Gene Name | interleukin 1 beta |
Database Link | |
Background | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008] |
Synonyms | IL-1; IL1-BETA; IL1F2 |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Alzheimer's disease, Apoptosis, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Graft-versus-host disease, Hematopoietic cell lineage, MAPK signaling pathway, NOD-like receptor signaling pathway, Prion diseases, Toll-like receptor signaling pathway, Type I diabetes mellitus |
Citations (5)
The use of this Antibodies has been cited in the following citations: |
---|
Gαq-PKD/PKCμ signal regulating the nuclear export of HDAC5 to induce the IκB expression and limit the NF-κB-mediated inflammatory response essential for early pregnancy
,null,
eLife
,PubMed ID 37498654
[IL1 beta]
|
Influence of hyperocclusion on the remodeling of gingival tissues
,Li, Y;Wang, Z;Liu, Y;Zhang, H;Huang, Y;Gao, P;Hu, Y;Xu, Q;,
International immunopharmacology
,PubMed ID 34153669
[IL1 beta]
|
Treponema pallidum promotes macrophage polarization and activates the NLRP3 inflammasome pathway to induce interleukin-1β production
,Lin, LR;Liu, W;Zhu, XZ;Chen, YY;Gao, ZX;Gao, K;Tong, ML;Zhang, HL;Xiao, Y;Li, WD;Li, SL;Lin, HL;Liu, LL;Fang, ZX;Niu, JJ;Lin, Y;Yang, TC;,
BMC Immunol.
,PubMed ID 30217146
[IL1 beta]
|
Duhuo Jisheng Decoction inhibits SDF-1-induced inflammation and matrix degradation in human degenerative nucleus pulposus cells in vitro through the CXCR4/NF-κB pathway
,Liu, ZC;Wang, ZL;Huang, CY;Fu, ZJ;Liu, Y;Wei, ZC;Liu, SG;Ma, C;Shen, JL;Duan, DD;,
Acta Pharmacol. Sin.
,PubMed ID 29795361
[IL1 beta]
|
Functional proteomics revealed IL-1ß amplifies TNF downstream protein signals in human synoviocytes in a TNF-independent manner
,Shen, S;Guo, J;Luo, Y;Zhang, W;Cui, Y;Wang, Q;Zhang, Z;Wang, T;,
Biochem. Biophys. Res. Commun.
,PubMed ID 24928389
[IL1 beta]
[Human; IHC] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF506443 | Carrier-free (BSA/glycerol-free) IL1B mouse monoclonal antibody, clone OTI3E1 (formerly 3E1) |
CNY 3,999.00 |
|
TA506443AM | IL1B mouse monoclonal antibody,clone 3E1, Biotinylated |
CNY 3,990.00 |
|
TA506443BM | IL1B mouse monoclonal antibody,clone 3E1, HRP conjugated |
CNY 3,990.00 |
|
TA506443S | IL1B mouse monoclonal antibody, clone OTI3E1 (formerly 3E1) |
CNY 800.00 |
其它IL1 beta产品