GADD45A Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2B7]

Specifications

Product Data
Clone Name	OTI2B7
Applications	WB
Recommend Dilution	WB 1:4000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human GADD45A(NP_001915) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	18.2 kDa
Gene Name	growth arrest and DNA damage inducible alpha
Database Link	NP_001915 Entrez Gene 13197 MouseEntrez Gene 25112 RatEntrez Gene 1647 Human UniProt ID P24522
Background	This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Synonyms	DDIT1; GADD45
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency
Protein Pathways	Cell cycle, MAPK signaling pathway, p53 signaling pathway

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