FGF 23 (FGF23) Rabbit Monoclonal Antibody [Clone ID: OTIR5D11]

Specifications

Product Data
Clone Name	OTIR5D11
Applications	WB
Recommend Dilution	WB 1:1000-1:5000
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human FGF23 (NP_065689) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
Predicted Protein Size	28 kDa
Gene Name	fibroblast growth factor 23
Database Link	NP_065689 Entrez Gene 8074 Human UniProt ID Q9GZV9
Background	This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013]
Synonyms	ADHR; FGFN; HFTC2; HPDR2; HYPF; PHPTC
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

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