ALK Rat Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3E7]
CAT#: TA801144BM
ALK rat monoclonal antibody,clone 3E7, HRP conjugated
Conjugation: Unconjugated Biotin
View other "OTI3E7" antibodies (4)
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CNY 3,990.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 4,840.00
Specifications
Product Data | |
Clone Name | OTI3E7 |
Applications | LMNX, WB |
Recommend Dilution | WB 1:2000 |
Reactivity | Human, Mouse, Rat |
Host | Rat |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human ALK (NP_004295) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | HRP |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 176.3 kDa |
Gene Name | anaplastic lymphoma receptor tyrosine kinase |
Database Link | |
Background | This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X). [provided by RefSeq, Jan 2011] |
Synonyms | CD246; NBLST3 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF801144 | Carrier-free (BSA/glycerol-free) ALK rat monoclonal antibody, clone OTI3E7 (formerly 3E7) |
CNY 3,999.00 |
|
TA801144 | ALK rat monoclonal antibody, clone OTI3E7 (formerly 3E7) |
CNY 1,999.00 |
|
TA801144AM | ALK rat monoclonal antibody,clone 3E7, Biotinylated |
CNY 3,990.00 |
|
TA801144S | ALK rat monoclonal antibody, clone OTI3E7 (formerly 3E7) |
CNY 800.00 |