beta 2 Microglobulin (B2M) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1A7]

Specifications

Product Data
Clone Name	OTI1A7
Applications	ELISA, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 21-119 of human B2M (NP_004039)produced in SF9 cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Gene Name	beta-2-microglobulin
Database Link	NP_004039 Entrez Gene 567 Human UniProt ID P61769
Background	This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia. [provided by RefSeq, Sep 2009]
Synonyms	IMD43
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Antigen processing and presentation

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