MEF2D Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1E11]

Specifications

Product Data
Clone Name	OTI1E11
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-282 of human MEF2D(NP_005911) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Predicted Protein Size	55.8 kDa
Gene Name	myocyte enhancer factor 2D
Database Link	NP_005911 Entrez Gene 17261 MouseEntrez Gene 81518 RatEntrez Gene 4209 Human UniProt ID Q14814
Background	This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Synonyms	DKFZp686I1536
Reference Data
Protein Families	Transcription Factors

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