p53 (TP53) Mouse Monoclonal Antibody [Clone ID: OTIpab 240]
CAT#: TA808657
p53 mouse monoclonal antibody,clone OTIpab 240
Size: 30 ul
Formulation: Carrier-Free
View other "OTIpab 240" antibodies (4)
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CNY 1,999.00
CNY 2,700.00
Cited in 3 publications. |
CNY 3,080.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 9,998.00
Specifications
Product Data | |
Clone Name | OTIpab 240 |
Applications | IHC |
Recommend Dilution | IHC 1:500 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Gel-purified p53-beta-galactosidase fusion protein containing murine p53 from aa 14-389 (derived from pSV53C cDNA clone). |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | tumor protein p53 |
Database Link | |
Background | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013] |
Synonyms | BCC7; LFS1; P53; TRP53 |
Reference Data | |
Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
Protein Pathways | Amyotrophic lateral sclerosis (ALS), Apoptosis, Basal cell carcinoma, Bladder cancer, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, Glioma, Huntington's disease, MAPK signaling pathway, Melanoma, Neurotrophin signaling pathway, Non-small cell lung cancer, p53 signaling pathway, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer, Thyroid cancer, Wnt signaling pathway |
Citations (3)
The use of this Antibodies has been cited in the following citations: |
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MDM2 induces EMT via the B‑Raf signaling pathway through 14‑3‑3
,Ou, M;Xu, X;Chen, Y;Li, L;Zhang, L;Liao, Y;Sun, W;Quach, C;Feng, J;Tang, L;,
Oncology reports
,PubMed ID 33955525
[TP53]
|
Clinicopathologic study on a rare variant of ameloblastoma with basal cell features
,You, Z;Sun, L;Yan, X;Zhang, J;Du, J;Li, T;Zhao, H;,
Oral Dis
,PubMed ID 30561173
[TP53]
|
Functional role of RRS1 in breast cancer cell proliferation
,Song, J;Ma, Z;Hua, Y;Xu, J;Li, N;Ju, C;Hou, L;,
J. Cell. Mol. Med.
,PubMed ID 30320499
[TP53]
|
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF808657 | Carrier-free (BSA/glycerol-free) p53 mouse monoclonal antibody,clone OTIpab 240 |
CNY 3,999.00 |
|
TA808657AM | p53 mouse monoclonal antibody,clone OTIpab 240, Biotinylated |
CNY 3,990.00 |
|
TA808657BM | p53 mouse monoclonal antibody,clone OTIpab 240, HRP conjugated |
CNY 3,990.00 |
|
TA808657S | p53 mouse monoclonal antibody,clone OTIpab 240 |
CNY 800.00 |