Collagen VI (COL6A1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1G8]

Specifications

Product Data
Clone Name	OTI1G8
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 752-835 of human COL6A1 (NP_001839) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	108.53 kDa
Gene Name	collagen type VI alpha 1
Database Link	NP_001839 Entrez Gene 12833 MouseEntrez Gene 294337 RatEntrez Gene 1291 Human UniProt ID P12109
Background	The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008]
Synonyms	BTHLM1; OPLL; UCHMD1
Reference Data
Protein Pathways	ECM-receptor interaction, Focal adhesion

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