CD105 (ENG) Mouse Monoclonal Antibody [Clone ID: UMAB290]

Specifications

Product Data
Clone Name	UMAB290
Applications	IHC, WB
Recommend Dilution	WB 1:1000, IHC 1:100
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human ENG(NP_000109) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Predicted Protein Size	67.78 kDa
Gene Name	endoglin
Database Link	NP_000109 Entrez Gene 2022 Human UniProt ID P17813
Background	This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
Synonyms	END; HHT1; ORW1
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.