STAT6 Rabbit Monoclonal Antibody [Clone ID: UMAB300]

CAT#: UM970005

STAT6 Rabbit monoclonal antibody,clone UMAB300

Size: 30 ul 100 ul



  View other "UMAB300" antibodies (1)

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CNY 1,430.00


货期*
2周

规格
    • 30 ul

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经常一起买 (3)
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Recombinant protein of human signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), 20 µg
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Transient overexpression lysate of signal transducer and activator of transcription 6, interleukin-4 induced (STAT6)
    • 100 ug

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Specifications

Product Data
Clone Name UMAB300
Applications IHC
Recommend Dilution IHC 1:1000,WB 1:5000
Reactivity Human
Host Rabbit
Clonality Monoclonal
Immunogen Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human STAT6 (NP_003144). The exact sequence is proprietary.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1.00mg/ml
Purification Purified from cell culture supernatant by affinity chromatography(protein A/G)
Conjugation Unconjugated
Predicted Protein Size 94.2 kDa
Gene Name signal transducer and activator of transcription 6
Background The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Synonyms D12S1644; IL-4-STAT; STAT6B; STAT6C
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors
Protein Pathways Jak-STAT signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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