STAT6 Rabbit Monoclonal Antibody [Clone ID: UMAB300]
CAT#: UM970005
STAT6 Rabbit monoclonal antibody,clone UMAB300
Size: 100 ul
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CNY 1,430.00
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Specifications
Product Data | |
Clone Name | UMAB300 |
Applications | IHC |
Recommend Dilution | IHC 1:1000,WB 1:5000 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Immunogen | Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human STAT6 (NP_003144). The exact sequence is proprietary. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1.00mg/ml |
Purification | Purified from cell culture supernatant by affinity chromatography(protein A/G) |
Conjugation | Unconjugated |
Predicted Protein Size | 94.2 kDa |
Gene Name | signal transducer and activator of transcription 6 |
Database Link | |
Background | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
Synonyms | D12S1644; IL-4-STAT; STAT6B; STAT6C |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors |
Protein Pathways | Jak-STAT signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
UM900005 | STAT6 Rabbit monoclonal antibody,clone UMAB300 |
CNY 3,600.00 |