Mouse VEGFR2/KDR ELISA Kit
CNY 5,330.00
货期*
3周
规格
Cited in 1 publication. |
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Specifications
Product Data | |
Description | Mouse VEGFR2/KDR ELISA Kit |
Size | 1 x 96 wells |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Mouse VEGFR2/KDR |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 62.5pg/ml-4000pg/ml |
Sample Type | Cell culture supernates and serum. |
Sample Volume | 100 ul |
Specificity | This kit is used for quantitative detection of mouse VEGFR2 |
Sensitivity | <2pg/ml |
Reactivity | Mouse |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | Vascular endothelial growth factor receptor 2(VEGFR-2) is a VEGF receptor. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It is mapped to 4q12. This gene encodes one of the two receptors of the VEGF. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. VEGF receptor 2 and the adherens junction act as shear-stress cotransducers, mediating the transduction of shear-stress signals into vascular endothelial cells. In addition to those, VEGFR-2 is also a positive functional marker defining stem cells and distinguishing them from progenitors. |
Gene Symbol | Kdr |
Citations (1)
The use of this Assay Kits has been cited in the following citations: |
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Anti-angiogenic effect of a chemically sulfated polysaccharide from Phellinus ribis by inhibiting VEGF/VEGFR pathway
,Ding, J;Jia, W;Cui, Y;Jin, J;Zhang, Y;Xu, L;Liu, Y;,
Int. J. Biol. Macromol.
,PubMed ID 32171839
[KDR]
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