Caspase 1 (CASP1) (NM_033295) Human 3' UTR Clone

CAT#: SC201105

3' UTR clone of caspase 1 apoptosis-related cysteine peptidase (interleukin 1 beta convertase) (CASP1) transcript variant epsilon for miRNA target validation



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CNY 4,845.00


货期*
3周

规格
    • 10 ug

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Firefly luciferase assay kit, 150 assays
    • 1 kit

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DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name Caspase 1 (CASP1) (NM_033295) Human 3' UTR Clone
Vector pMirTarget
Synonyms ICE; IL1BC; P45
ACCN NM_033295
Insert Size 119 bp
Sequence Data
>SC201105 3' UTR clone of NM_033295
The sequence shown below is from the reference sequence of NM_033295. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon


CAATTGGCAGAGCTCAGAATTCAAGCGATCGC

CTACCTCTTCCCAGGACATTAAAATAAGGAAACTGTATGAATGTCTGTGGGCAGGAAGTGAAGAGATCCT
TCTGTAAAGGTTTTTGGAATTATGTCTGCTGAATAATAAACTTTTTTGA

ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_033295.2
Synonyms ICE; IL1BC; P45
Summary This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012]
Locus ID 834
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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