MICA (NM_000247) Human 3' UTR Clone
CAT#: SC201814
3' UTR clone of MHC class I polypeptide-related sequence A (MICA) for miRNA target validation
Need custom modification / cloning service?
Get a free quote
CNY 4,845.00
货期*
3周
规格
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
经常一起买 (2)
Specifications
Product Data | |
Product Name | MICA (NM_000247) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | MIC-A; PERB11.1 |
ACCN | NM_000247 |
Insert Size | 206 bp |
Sequence Data |
>SC201814 3’UTR clone of NM_000247
The sequence shown below is from the reference sequence of NM_000247. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGGTCCACTGGCTCCACTGAGGGCGCCTAGACTCTACAGCCAGGCAGCTGGGATTCAATTCCCTGCCTG GATCTCACGAGCACTTTCCCTCTTGGTGCCTCAGTTTCCTGACCTATGAAACAGAGAAAATAAAAGCAC TTATTTATTGTTGTTGGAGGCTGCAAAATGTTAGTAGATATGAGGCGTTTGCAGCTGTACCATATTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_000247.3 |
Synonyms | MIC-A; PERB11.1 |
Summary | This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
Locus ID | 100507436 |
MW | 7.4 |
Documents
Product Manuals |
FAQs |
Resources
Customer
Reviews
Loading...