PIG3 (TP53I3) (NM_147184) Human 3' UTR Clone

Specifications

Product Data
Product Name	PIG3 (TP53I3) (NM_147184) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	PIG3
ACCN	NM_147184
Insert Size	176 bp
Sequence Data	Insert Sequence (showhide) >SC201833 3’UTR clone of NM_147184 The sequence shown below is from the reference sequence of NM_147184. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGCAAGATCGTCCTGGAACTGCCCCAGTGAAGGAGGATGGGGCAGGACAGGACGCGGCCACCCCAGGCC TTTCCAGAGCAAACCTGGAGAAGATTCACAATAGACAGGCCAAGAAACCCGGTGCTTCCTCCAGAGCCG TTTAAAGCTGATATGAGGAAATAAAGAGTGAACTGGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_147184.4
Synonyms	PIG3
Summary	The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Locus ID	9540
MW	7

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