Slingshot homolog 1 (SSH1) (NM_001161331) Human 3' UTR Clone

Specifications

Product Data
Product Name	Slingshot homolog 1 (SSH1) (NM_001161331) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	SSH1L
ACCN	NM_001161331
Insert Size	231 bp
Sequence Data	Insert Sequence (showhide) >SC202256 3’UTR clone of NM_001161331 The sequence shown below is from the reference sequence of NM_001161331. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAGGGACCTGAGGGTTCTTTCACAGGGTGATTCTGCTGGTGGGTACGTAGTGCATACCTTATATAGCAA ATTGAGAATCTGTTGGGAATAACACATATCTCTGCACACCATCTTCACCCCATGTACCTTATTCATACC CTGGGCAGGGCTTCCAACTCAATTTCTTTTTGTGTATGTAAAATTAAAACATATAATTTATCAGCCAAC TTCAAAAAAAAAAAAAAAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001161331.1
Synonyms	SSH1L
Summary	The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Locus ID	54434
MW	8.8

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