CDK4 (NM_000075) Human 3' UTR Clone

Specifications

Product Data
Product Name	CDK4 (NM_000075) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CMM3; PSK-J3
ACCN	NM_000075
Insert Size	828 bp
Sequence Data	Insert Sequence (showhide) >SC204448 3’UTR clone of NM_000075 The sequence shown below is from the reference sequence of NM_000075. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTACATAAGGATGAAGGTAATCCGGAGTGAGCAATGGAGTGGCTGCCATGGAAGGAAGAAAAGCTGCCA TTTCCCTTCTGGACACTGAGAGGGCAATCTTTGCCTTTATCTCTGAGGCTATGGAGGGTCCTCCTCCAT CTTTCTACAGAGATTACTTTGCTGCCTTAATGACATTCCCCTCCCACCTCTCCTTTTGAGGCTTCTCCT TCTCCTTCCCATTTCTCTACACTAAGGGGTATGTTCCCTCTTGTCCCTTTCCCTACCTTTATATTTGGG GTCCTTTTTTATACAGGAAAAACAAAACAAAGAAATAATGGTCTTTTTTTTTTTTTTAATGTTTCTTCC TCTGTTTGGCTTTGCCATTGTGCGATTTGGAAAAACCACTTGGAAGAAGGGACTTTCCTGCAAAACCTT AAAGACTGGTTAAATTACAGGGCCTAGGAAGTCAGTGGAGCCCCTTGACTGACAAAGCTTAGAAAGGAA CTGAAATTGCTTCTTTGAATATGGATTTTAGGCGGGGCGTGGTGGCTCACGCCTATAATCCCAGCACGT TGGGAGGCCAACGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGACTAACATGGTGAAAC CCTGTCTCTACTAAAAATACAAAATTAGTCAGGCGTGGTGGTGCACACCTGTAATCCCAGCTACTTGGG AGACTGAGGCAGGAGGATCGCTTGAACCCGGGAGGCAGAGGTTGCGGTGAGCCGAGATCATGCCATTGC ACTCCAGCCTGGGCAACAGAGCAAGACTCTGTGTCAAAAAAAAAAAAAGAATATAGATTTTTAAATGGC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000075.4
Synonyms	CMM3; PSK-J3
Summary	The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008]
Locus ID	1019
MW	31.6

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